Non-structural protein 6 nsp6

UniProt ITasser SWISS Models alphafold D3Targets-2019-nCoV

Plays a role in the initial induction of autophagosomes from host reticulum endoplasmic. Later, limits the expansion of these phagosomes that are no longer able to deliver viral components to lysosomes


No model built for protein with good structural coverage represented in PDB

Models/PDB Model Chains_ID Selected Templates Model-Quality (MolProbity) PDB Coverage Model Coverage Sequence Length Oligomer States Oligomer Interfaces Model information
nsp6 A AlphaFold Prediction 0.85 0.00% 100.00% 290 monomer



Binding Site Predictions

The fpocket calculation in this table only for structure present in the Model/PDB table above.

fpocket pocket score drug score hydrophobicity score polarity score
pocket0_nsp6 38.78 0.87 41.47 10
pocket1_nsp6 30.02 0.3 31.17 11
pocket2_nsp6 24.86 0.84 52.8 5
pocket0_nsp6 20.05 0.07 19.5 7

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Protein-Protein Interactions

We have mapped SARS CoV-2 human Protein-Protein Interactions from A SARS-CoV-2 protein interaction map reveals targets for drug repurposing human drug target interacted with SARS CoV-2 are highlighted in black arrow.

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