SARS-CoV-2 3D

Non-structural protein 4 nsp4

Participates in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication

No model built for protein with good structural coverage represented in PDB

Models/PDB	Model Chains_ID	Selected Templates	Model-Quality (MolProbity)	PDB Coverage	Model Coverage	Sequence Length	Oligomer States	Oligomer Interfaces	Model information
nsp4 Download Pdb file	A,B	1BCP_F; 3VC8_A; 3A7K_A; 1T70_A;	3.18	0.00%	100.00%	500	Homo 2-mer	nsp4 Download interfaces pdf	nsp4 Download model information txt

Models/PDB

Model Chains_ID

Selected Templates

Model-Quality (MolProbity)

PDB Coverage

Model Coverage

Sequence Length

Oligomer States

Oligomer Interfaces

Model information

nsp4

A,B

1BCP_F; 3VC8_A; 3A7K_A; 1T70_A;

3.18

0.00%

100.00%

500

Homo 2-mer

nsp4

nsp4

The fpocket calculation in this table only for structure present in the Model/PDB table above.

fpocket	pocket score	drug score	hydrophobicity score	polarity score
pocket0_nsp4	44.24	0.89	43.62	22
pocket1_nsp4	43.44	0.88	43.62	22
pocket2_nsp4	25.47	0.06	21.31	24
pocket3_nsp4	23.27	0.04	18.42	22
pocket4_nsp4	19.22	0.02	10.26	17
pocket5_nsp4	18.52	0.02	6.23	17
pocket6_nsp4	16.84	0.32	29.39	11
pocket7_nsp4	13.47	0.02	18.48	15
pocket8_nsp4	12.17	0.14	28.5	11
pocket9_nsp4	10.43	0.02	19.7	11
pocket10_nsp4	10.01	0.15	46.76	8
pocket11_nsp4	9.14	0.38	33.41	5
pocket12_nsp4	9.14	0.21	52.16	8

We have mapped SARS CoV-2 human Protein-Protein Interactions from A SARS-CoV-2 protein interaction map reveals targets for drug repurposing human drug target interacted with SARS CoV-2 are highlighted in black arrow.