UniProt ITasser SWISS Models alphafold D3Targets-2019-nCoV

May play a role in host-virus interaction


No model built for protein with good structural coverage represented in PDB

Models/PDB Model Chains_ID Selected Templates Model-Quality (MolProbity) PDB Coverage Model Coverage Sequence Length Oligomer States Oligomer Interfaces Model information
X-RAY_7JT1 A,B 7JTL; Solved experimentally with good Coverage 1.94 100.00% 0.00% 121 Homo 2-mer



Binding Site Predictions

The fpocket calculation in this table only for structure present in the Model/PDB table above.

fpocket pocket score drug score hydrophobicity score polarity score
pocket1_ORF8 30.3141 0.3114 38 3
pocket0_ORF8 31.3744 0.6606 39 4
pocket5_ORF8 14.6802 0.0186 17.25 5
pocket4_ORF8 16.946 0.103 31.0833 8
pocket2_ORF8 29.8776 0.1052 33.7692 7
pocket3_ORF8 18.9628 0.0395 19.4167 7
pocket5_ORF8 7.37 0.03 28.66 3

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Other PDB Hits

ID Method Resolution Å Chains Links
7jtl X-RAY 2.04 A, B PDBe
7jx6 X-RAY 1.61 A, B; PDBe

Protein-Protein Interactions

We have mapped SARS CoV-2 human Protein-Protein Interactions from A SARS-CoV-2 protein interaction map reveals targets for drug repurposing human drug target interacted with SARS CoV-2 are highlighted in black arrow.

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