UniProt ITasser SWISS Models alphafold D3Targets-2019-nCoV

Could be a determinant of virus virulence, since, when expressed in an otherwise attenuated JHM strain of murine coronavirus, it can dramatically increase the lethality of the latter. Seems to stimulate cellular DNA synthesis in vitro


No model built for protein with good structural coverage represented in PDB

Models/PDB Model Chains_ID Selected Templates Model-Quality (MolProbity) PDB Coverage Model Coverage Sequence Length Oligomer States Oligomer Interfaces Model information
ORF6 A 4GQT_A 2.37 0.00% 100.00% 61 monomer



Binding Site Predictions

The fpocket calculation in this table only for structure present in the Model/PDB table above.

fpocket pocket score drug score hydrophobicity score polarity score
pocket0_ORF6 30.74 0.44 44.43 2

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Protein-Protein Interactions

We have mapped SARS CoV-2 human Protein-Protein Interactions from A SARS-CoV-2 protein interaction map reveals targets for drug repurposing human drug target interacted with SARS CoV-2 are highlighted in black arrow.

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