Could be a determinant of virus virulence, since, when expressed in an otherwise attenuated JHM strain of murine coronavirus, it can dramatically increase the lethality of the latter. Seems to stimulate cellular DNA synthesis in vitro
No model built for protein with good structural coverage represented in PDB
The fpocket calculation in this table only for structure present in the Model/PDB table above.
|fpocket||pocket score||drug score||hydrophobicity score||polarity score|
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We have mapped SARS CoV-2 human Protein-Protein Interactions from A SARS-CoV-2 protein interaction map reveals targets for drug repurposing human drug target interacted with SARS CoV-2 are highlighted in black arrow.